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Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but They may be unheard of in this malignancy in comparison with other lymphoid neoplasms. CHD2 is mutated in 5% of CLL and 7% of MBL.75 The histone methyltransferase SETD2 and ARID1A are also mutated in a little proportion of sufferers. Of Be aware, MYD88